Joseph told reporters in Washington that the United States believes Iran is now moving quickly to establish its nuclear program.
"It's fair to say, I believe, that the Iranians have put both feet on the accelerator. They're moving very quickly to establish new realities on the ground, associated with their nuclear program," Joseph said.
Another senior U.S. diplomat, Nicholas Burns, called on Russia to cancel a planned sale of air defense missile systems to Iran because of Iran's nuclear development.
The Russian government has reiterated that it remains opposed to sanctions on Iran at the current time.
Iran denies any efforts to make nuclear arms.
(compiled from agency reports)