In comments made to the independent uznews.net website, Tolib Yaqubov says Europe would be making a "great mistake" if it resumed dialog with Uzbekistan.
"To engage in a dialog with Karimov is like feeding a dragon which only gets fatter, more insatiable, and more bloodthirsty," Yaqubov says, according to uznews.net.
He warns that talks with Turkmen President Saparmurat Niyazov would serve the same purpose.
The EU's current restrictions include an arms embargo and a visa ban on Uzbek officials blamed for the violent death of dozens, if not hundreds, of Andijon residents.
Aftermath Of Andijon
A dedicated webpage bringing together all of RFE/RL's coverage of the events in Andijon, Uzbekistan, in May 2005 and their continuing repercussions.